EHS 260 Lecture Notes - Lecture 30: International Diabetes Federation, Diabetes Mellitus Type 2, Diabetes Mellitus Type 1
Document Summary
Diabetes mellitus is characterized by chronic hyperglycemia (high blood glucose concentration) and high nefa (non-esterified fatty acid) concentration. Over time high blood glucose and nefa concentrations may lead to a variety of complications which impair quality of life and reduce life expectancy. Autoimmune destruction of pancreatic -cells in islets of langerhan. Insensitivity to insulin (insulin resistance for a given concentration of insulin, less glucose is cleared from the blood cells). Usually found in obese or overweight adults. Was typically associated with obese adults age 40+, but is becoming much more frequent in children. While genes play a role, 80% preventable with healthy diet and pa (international diabetes. Lifetime risk of developing dm in us (born in 2000) Although type 2 diabetes was previously considered an adult-onset disease, it is now clear that it also occurs in children and adolescents as evidenced by a growing number of reports from many countries world-wide.