CHEM 451 Lecture Notes - Lecture 5: Beta Sheet, Alpha Helix, Valine
Document Summary
Side chains tend to point to n terminus of helix, so +ve charged ____ points in direction of dipole. Don"t get lots of side chain interactions in alpha helices, not that it"s a feature that you xpect ofr side chains to interact with each other. Don"t expect them to interact with each other, because one is charged and other is hydrophobic. Sequence is similar to the one before because ___ make good helices. Tyr is used for absorbance to see the structure, aromaticity. Spacing of 5 vs 4 reisudes -> higher ellipticity, so it"s more favourable when there are 4 residues as opposed to i+5. I+4 spacing for residues in context of helix allows for alignment on top of each other. I+5 now shifts things outwards, it"s improtnat that htey are on same side of helix -> no stability between helices. If they switch the position so lysine then valine -> not the same effect.
