BSCI-1510 Lecture Notes - Lecture 33: Endonuclease, Phosphodiester Bond, Adenine
4 Apr 2016
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Document Summary
Processing events that occur of the nascent (primary transcript). A. capping: the 5" cap. capping reaction occurs in the following way: Gtp at the 5" end of the nascent rna. By capping enzyme forms 5" cap on the rna that"s being made. the 5" cap consists of a g residue that had an unusual linkage. 5"-5" linkage with 3 phosphates the g residue is methylated. The function of the cap: protect the rna from 5" exonucleases. It is a binding site for translational machinery this allows the cap to function in the initiation of translation. Rna doesn"t stay unassociated with anything else. it gets packaged (analogous to packaging of. 5" exon beginning of intron end of intron 3" exon. 5" splice site branch point 3" splice site snrnps through rna recognize and bind to those consensus sequences: the second steps, snrnp recruit spliceosome proteins to build a functional spliceosome.
