KINE 304 Lecture Notes - Lecture 6: Steroid, Adrenal Medulla, Beta Cell

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Functions regulated by 2 major systems: nervous system, endocrine system mainly controls metabolic functions of body, * effects of some hormones occur in seconds, other hormones continue to regulate function for weeks. Hormones produced and released by endocrine glands, carried away by blood, and then affect target cells: * in some cases 2 or more endocrine glands work together as axis . Some endocrine glands also perform other important physiologic functions: ex: heart, pancreas, hypothalamus. Single endocrine gland may secrete more than 1 hormone, but single cell type secretes only 1 type of hormone. Amine hormones derived from tyrosine, include thyroid hormones, and catecholamines. Peptide hormones undergo extensive processing before secretion: preprohormones (ribosome) prohormone (er) hormone (golgi apparatus), then stored in vesicles and leave via exocytosis, *peptide hormones are readily soluble in plasma, example: insulin, gh, glucagon, acth. Steroid hormones all derived from cholesterol: specific steroidogenic enzymes contained by cell determines which steroids ultimately produced.

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