Pathology 3500 Lecture 3: part 1
Document Summary
Additional learning resources: robbins basic pathology, 10th edition, chapter 3, acute inflammation: http://www. youtube. com/watch?v=suckm97yvyk. Acute inflammation: vascular events, cellular events, chemical mediators of inflammation, morphological patterns of acute inflammation, outcomes of acute inflammation. Agents (i. e. infection) physical agents (heat, cold) According to duration and histological appearance, inflammation is called: acute: short duration; pmns; exudation, chronic: longer duration; lymphocytes & macrophages; tissue repair. The complex series of events which occur in the acute inflammatory reaction include vascular changes, cellular events and mediation by chemical substances. They are all intimately related, but for the purposes of clarity they are discussed separately. 2: vascular events, transient vasoconstriction of arterioles, vasodilatation, first of arterioles and then the remaining microcirculation. We know of at least 6 mechanisms by which the endothelium becomes leaky during inflammation. All of these mechanisms probably contribute to varying degrees in response to stimuli: endothelial cell contraction leading to wide intercellular gaps.
