MBB 222 Lecture 17: Lecture 17, 18 notes
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Abriefreview and further introductionto enzymes proteinsdomost of work in the ceil theywork byinteractingwiothermole they areessentialfor life andnecessaryfor an cei processes. Enzymes almosteverybiochemical run is catalyzed by an enzyme. Enzymeshaveextraordinary catalyticpower ishighlyspecific inacceleration of chemical run in act in aqueousenvironments w mildtemp and ph physiological conditions w the exception of catalyticrivas ribozyme au enzymes are protein classification of enzymes. Mostenzymes catalyze the transfer of e atoms or functional group. Theyare therefore classified according to thetype of transfer ran the groupdonor the groupacceptor. Manyenzymenameshave exdivapolymerasecatalyzes the polymerization of dna ase urease catalyzes the hydrolysis of urea. Enzymesenhance rates by lowering out theactivation e for the transition statet. Og is the activation e barrier bit s and p. E required for alignment ofreacting groups formation oftransientunstablecharges bondrearrangement and other changes for the run to proceed in either direction some generalstrategies for enzyme catalysis. Someenzymes function to bring substrates into closeproximity and inthe correct orientation to allowwins to occur.