Physiology 3140A Lecture 2: Toolbox Proteins

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Proteins that are released by plasma cells (type of immune cell) when foreign cells (antigens) enter the body. There are 5 diff main kinds of antibodies. Diff antibodies are identified by variations in their light and heavy chains. Diff antibodies will have different variations in their chains. The variation will determine which specific antigen it will bind to. The corresponding antigen binds to either tip of the coiled chain. B lymphocyte are immune cells that have antibodies on their surface. When an antigen binds the antibody, this causes the lymphocyte to become a. The plasma cell (post lymphocyte) can then release the antibodies on its surface and produce even more antibodies to release into the blood. Protein on the surface of a forgein virus. Antibodies, like any protein, would be digested. Ex. omalizumab is given subcutaneously (under skin) and used to treat asthma. Testing for antibodies to identify how many people have been infected.