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HN210 Lecture Notes - Lecture 7: Spasm, Diazepam, Multiple Sclerosis

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lucidz
23 Mar 2023
School
WLU
Department
Health Sciences
Course
HN210
Professor

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Document Summary

Uses, and side effects of the medication lesson 24: what. Uses, and side effects of the medication diazepam is a medicine that is available only with a doctor"s prescription and is a member of the benzodiazepine family of medications. It is often used in the treatment of anxiety disorders, as well as alcohol withdrawal and muscular spasms. In order for diazepam to be effective, it must first raise the level of activity of the neurotransmitter known as gamma-aminobutyric acid (gaba) in the brain. This, in turn, helps to relax the central nervous system. One of diazepam"s many applications is as a therapy for anxiety disorders. These conditions are distinguished by the presence of sensations of excessive concern or dread, which might get in the way of normal day-to-day activity. Diazepam"s ability to relax the central nervous system may be helpful in alleviating some of these sensations.

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Related Questions

What are prions?

In cell, there are subcellular organelles. They are not full organism. Prions are just proteins. They don't have any other macromolecules. Prions have capacity to form copies through replication. They replicate through free radical and chain mechanism. 

Doctor Stainly pruisne work on prions and show it's relation with disease called mad cow disease. ( This is neurodegenerative disease and responsible for harmful effects on brain).

In Australia sheep was infected with prions, caused scarpie disease in sheep. Organs of sloghed sheep were used in cow feedd. When cow consume feed, prions were transmitted to cow and cow start to show unusual behavior.

Symptoms of prions infection are like that of some disease 

  1. Kurulyprosy
  2. Insomnia
  3. Dimensia

Detection of prions: Prions can be detected by Western bloting.

Normal prions:

Normal prions are present in our body. They don't have tendency to form rigid aggregate. They are quite less in number. They have following functions

  1. Cellular differentiation
  2. Store elemental surplus that is used in future
  3. Memory enhancement

Molecular basis of prions:There is some difference in structure of Normal and abnormal prions.

  1.  Normal prions have molecular weight 33-35KD while abnormal prions have molecular weight 27-30KD
  2. In normal prions at position 178 amino acid aspartate is present while in abnormal prions at 178 position asparagine is present. 

Prions diagnosis and analysis:

  1. Brain biopsy....in past for taking sample brain biopsy was used but now a days tonsils biopsy is used for sampling.

Immuno fluorescence:Biopsy sample is taken on slide and it is treated with antibody ( of abnormal prions) which is against normal prions. Speciality of antibody is that when it bind with abnormal prion it will glow. If we capture fluroscene it's mean abnormal prion is present in sample. As abnormal prion antibody was label with fluroscene probe. So patient sample will show fluroscene while normal sample will not show fluroscene.

Transmission of prions: Normally prions can't Cross specie barrier they transmitted through different ways. Like as formite

If a person is effected with prions and he has wound in head and his comb is used by another person so prions can be transferred to other individual. Comb is Carrier of prion.

Prions are very slow acting immune system can't destroy them.

 

 

Contents of mypubspec.yaml - I was told by someone from OneClass that this mypubspec.yaml was invalid. Which didn't make any sense to me.

 

 

name: todo_list1 description: A new Flutter project. # The following line prevents the package from being accidentally published to # pub.dev using `flutter pub publish`. This is preferred for private packages. publish_to: 'none' # Remove this line if you wish to publish to pub.dev
# The following defines the version and build number for your application. # A version number is three numbers separated by dots, like 1.2.43 # followed by an optional build number separated by a +. # Both the version and the builder number may be overridden in flutter # build by specifying --build-name and --build-number, respectively. # In Android, build-name is used as versionName while build-number used as versionCode. # Read more about Android versioning at # In iOS, build-name is used as CFBundleShortVersionString while build-number is used as CFBundleVersion. # Read more about iOS versioning at # # In Windows, build-name is used as the major, minor, and patch parts # of the product and file versions while build-number is used as the build suffix. version: 1.0.0+1
environment:   sdk: '>=2.19.3 <3.0.0'
# Dependencies specify other packages that your package needs in order to work. # To automatically upgrade your package dependencies to the latest versions # consider running `flutter pub upgrade --major-versions`. Alternatively, # dependencies can be manually updated by changing the version numbers below to # the latest version available on pub.dev. To see which dependencies have newer # versions available, run `flutter pub outdated`. dependencies:   flutter:     sdk: flutter

  # The following adds the Cupertino Icons font to your application.   # Use with the CupertinoIcons class for iOS style icons.   cupertino_icons: ^1.0.2
dev_dependencies:   flutter_test:     sdk: flutter   yamlCopy code dependencies:     hive_flutter: ^1.1.0
  # The "flutter_lints" package below contains a set of recommended lints to   # encourage good coding practices. The lint set provided by the package is   # activated in the `analysis_options.yaml` file located at the root of your   # package. See that file for information about deactivating specific lint   # rules and activating additional ones.   flutter_lints: ^2.0.0
# For information on the generic Dart part of this file, see the # following page:
# The following section is specific to Flutter packages. flutter:
  # The following line ensures that the Material Icons font is   # included with your application, so that you can use the icons in   # the material Icons class.   uses-material-design: true
  # To add assets to your application, add an assets section, like this:   # assets:   #   - images/a_dot_burr.jpeg   #   - images/a_dot_ham.jpeg
  # An image asset can refer to one or more resolution-specific "variants", see   #
  # For details regarding adding assets from package dependencies, see   #
  # To add custom fonts to your application, add a fonts section here,   # in this "flutter" section. Each entry in this list should have a   # "family" key with the font family name, and a "fonts" key with a   # list giving the asset and other descriptors for the font. For   # example:   # fonts:   #   - family: Schyler   #     fonts:   #       - asset: fonts/Schyler-Regular.ttf   #       - asset: fonts/Schyler-Italic.ttf   #         style: italic   #   - family: Trajan Pro   #     fonts:   #       - asset: fonts/TrajanPro.ttf   #       - asset: fonts/TrajanPro_Bold.ttf   #         weight: 700   #   # For details regarding fonts from package dependencies,   # see
Hi I fixed the material dart issue - https://oneclass.com/question/7345764-dont-understand-why-this-packa.en.html
By following people suggestions and also committed the pubspec.yaml file.
That error msg wasn't there before until I made change to fix the material.dart issue.
But now I'm getting that same error msg for
import 'package:final_project1/second.dart';
See screenshot at the bottom.
import 'package:flutter/material.dart';
import 'dart:core';
import 'package:final_project1/second.dart';
//test
void main() {
runApp(const App());
}

My pubspec.yaml - name: final_project1
description: Food Ordering

# The following line prevents the package from being accidentally published to
# pub.dev using `flutter pub publish`. This is preferred for private packages.
publish_to: 'none' # Remove this line if you wish to publish to pub.dev

# The following defines the version and build number for your application.
# A version number is three numbers separated by dots, like 1.2.43
# followed by an optional build number separated by a +.
# Both the version and the builder number may be overridden in flutter
# build by specifying --build-name and --build-number, respectively.
# In Android, build-name is used as versionName while build-number used as versionCode.
# Read more about Android versioning at https://developer.android.com/studio/publish/versioning
# In iOS, build-name is used as CFBundleShortVersionString while build-number is used as CFBundleVersion.
# Read more about iOS versioning at
# https://developer.apple.com/library/archive/documentation/General/Reference/InfoPlistKeyReference/Articles/CoreFoundationKeys.html
# In Windows, build-name is used as the major, minor, and patch parts
# of the product and file versions while build-number is used as the build suffix.
version: 1.0.0+1

environment:
sdk: '>=2.17.1 <3.0.0'

# Dependencies specify other packages that your package needs in order to work.
# To automatically upgrade your package dependencies to the latest versions
# consider running `flutter pub upgrade --major-versions`. Alternatively,
# dependencies can be manually updated by changing the version numbers below to
# the latest version available on pub.dev. To see which dependencies have newer
# versions available, run `flutter pub outdated`.
dependencies:
flutter:
sdk: flutter
# Add the dependency
flutter_material: material.dart

# The following adds the Cupertino Icons font to your application.
# Use with the CupertinoIcons class for iOS style icons.
cupertino_icons: ^1.0.2

dev_dependencies:
flutter_test:
sdk: flutter

# The "flutter_lints" package below contains a set of recommended lints to
# encourage good coding practices. The lint set provided by the package is
# activated in the `analysis_options.yaml` file located at the root of your
# package. See that file for information about deactivating specific lint
# rules and activating additional ones.
flutter_lints: ^2.0.0

# For information on the generic Dart part of this file, see the
# following page: https://dart.dev/tools/pub/pubspec

# The following section is specific to Flutter packages.
flutter:

# The following line ensures that the Material Icons font is
# included with your application, so that you can use the icons in
# the material Icons class.
uses-material-design: true

# To add assets to your application, add an assets section, like this:
assets:
- images/


# An image asset can refer to one or more resolution-specific "variants", see
#

# For details regarding adding assets from package dependencies, see
#

# To add custom fonts to your application, add a fonts section here,
# in this "flutter" section. Each entry in this list should have a
# "family" key with the font family name, and a "fonts" key with a
# list giving the asset and other descriptors for the font. For
# example:
# fonts:
# - family: Schuyler
# fonts:
# - asset: fonts/Schuyler-Regular.ttf
# - asset: fonts/Schuyler-Italic.ttf
# style: italic
# - family: Trajan Pro
# fonts:
# - asset: fonts/TrajanPro.ttf
# - asset: fonts/TrajanPro_Bold.ttf
# weight: 700
#
# For details regarding fonts from package dependencies,
# see


pubspec.yaml screenshot below