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29 Oct 2018

Why do diseases like Down Syndrome occur in meiosis and not mitosis when nondisjunction can occur in both processes?

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31 Oct 2018

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A man with normal vision and a woman who is colorblind have a child with Klinefelter's syndrome and normal vision. Did nondisjunction occur in the mother or the father? Did nondisjunction occur in meiosis I or meiosis II?

Question 3 options:

	father; meiosis I
	father; meiosis II
	mother, meiosis I
	mother; meiosis II

Occurence of many diseases caused by faulty genetics, such as down sydrome, the cause of the disease is due to an extra chromosome. Why would this extra chromosome mutation occur in meiosis rather than mitosis? Why? (no need to give general background of meiosis or mitosis) Include information on daughter cells and how they're not passed laterally. 200 words minimum please.

carminemacaw684

-Complete the following sentences: metaphase of mitosis, prophase II of meiosis, crossing over, anaphase I of meiosis, variable, random fertilization, identical, random orientation, metaphase I of meiosis, prophase I of meiosis, metaphase II of meiosis, reduction division

Two processes that occur during meiosis produce genetically ____________ cells.

In a process called ____________ , paired homologous chromosomes align randomly at the cell equator. This occurs during this stage of cell division: ____________ .

In a process called ____________ , genetic material is exchanged between homologous chromosomes. This occurs during this stage of cell division: ____________ .

-Complete the following paragraph to describe nondisjunction and the resulting effects on chromosome number.

words: euploidy, primary nondisjunction, nomal, nondisjunction, secondary nondisjunction, homologous chromosomes, abnormal, trisomy, monosomy, sister chromatids, aneuploid

1.During meiosis I, ____________ separate and move towards opposite ends of the poles.

2.During meiosis II, ____________ separate and move towards opposite ends of the poles.

3.During meiosis I, if both members of a homologous pair go into the same daughter cell, ____________ is said to occur and no normal gametes are produced.

4.During meiosis II, if the sister chromatids fail to separate and both daughter chromosomes go into the same gamete, ____________ is said to occur. Half the gametes are aneuploid while the other half are euploid.

5.If an egg that contains 24 chromosomes instead of 23 chromosomes is fertilized by a normal sperm, ____________ is said to have occurred.

6.If an egg that contains 22 chromosomes instead of 23 chromosomes is fertilized by a normal sperm, ____________ is said to have occurred.

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Why do diseases like Down Syndrome occur in meiosis and not mitosis when nondisjunction can occur in both processes?

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