How is the structure of DNA and the genome related to the various mechanisms of transcriptional regulation? Discuss examples at distinct levels of organization. Answer in approximately 300 words.

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How are the distinct translation initiation mechanisms in prokaryotes and eukaryotes related to mRNA structure, and what does this suggest about potential regulatory strategies in each? Answer in approximately 300 words.

Escargot is known to act primarily as a transcriptional repressor. The way that Escargot represses transcription is by binding to specific sequences near its target genes, and recruiting to DNA a series of histone de-acetylases. Knowing what you now know about the molecular mechanisms of transcriptional regulation in eukaryotes, please explain how Escargot functions within cells (in 150 words or fewer). Pretend that you are talking to a bio student who hasn't studied the molecular mechanisms of transcriptional regulation yet.

12. Discuss and distinguish between ways that cells regulate expression of genes at the transcriptional and translational levels, providing at least one specific example of each type of regulation. For transcriptional regulation, describe the type of chromatin structures and location in the nucleus that you would expect to find this type of regulation occurring. For translational regulation, describe the location in the cell that this level of regulation most likely occurs.

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How is the structure of DNA and the genome related to the various mechanisms of transcriptional regulation? Discuss examples at distinct levels of organization. Answer in approximately 300 words.

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