i) Recombinant Inbred Line.
How is it created?
What is the relative percentage of recombination present within the genome in the lines?
What are the advantages and disadvantages of using it for gene mapping?
i) Recombinant Inbred Line.
How is it created?
What is the relative percentage of recombination present within the genome in the lines?
What are the advantages and disadvantages of using it for gene mapping?
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Q.) A geneticist is mapping the location of three markers relative to a disease causing genetic variant. Her results are shown below. Based on the results of the mapping, answer the following questions.
Marker | Recombination fraction relative to disease gene |
X | 0.3 |
Y | 0.5 |
Z | 0.1 |
a.) Which marker is closest to the disease-causing genetic variant? Support your answer. (2)
b.) Which marker is not linked to the disease-causing variant? Support your answer. (2)
c.) If the geneticist scored 200 chromosomes for recombination, how many recombinants did she observe for each marker? (2)