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chocolatesheep347Lv1

28 Sep 2019

In Americans, the frequency of albinism is 1 in 20,000 people
(1 / 20,000 = 0.00005). Albinism is a recessive disease (singlegene, 2 alleles).What is the ratio of heterozygous carriers ofalbinism to homozygous recessive individuals (i.e. people withalbinism)?
The answer is: 281: 1
My question is in regards to how to solve this problem utilizingthe Hardy Weinberg Equation( Assign phenotypes to each of p^2, 2pq,and q^2.)

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Beverley SmithLv2

28 Sep 2019

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Hardy-Weinberg Equilibrium Problems

p is the frequency of the dominant allele in the population

q is the frequency of the recessive allele in the population

p2 is the frequency of the homozygous dominant genotype

q2 is the frequency of the homozygous recessive genotype

2pq is the frequency of the heterozygous genotype

p + q = 1

p2 + 2pq + q2 = 1 Find q2 ï q ï p ï p2 ï 2pq

A rare disorder of cystic fibrosis (characterized by abnormal transport ofchloride and sodium across an epithelium, leading to thick, viscous secretions) occurs every 1 in 3,300 births. To express this trait one must be homozygous recessive (ff).

The cystic fibrosis allele is represented by f. The normal allele is F. Suppose both parents have alleles Ff. The possible combinations of alleles in the children are FF, Ff, Ff and ff. The alleles ff will cause the disease. So, although the parents do not have cystic fibrosis, they can produce children with the disease. The parents are called 'carriers' of the disease

What is the frequency of the population that carries the trait? (Ff)

1. Phenylketonuria is a severe form of mental retardation caused by a homozygous recessive allele. This condition affects about 1 in 10,000 newborn Caucasians. Estimate the frequency of the carriers for this allele in the population assuming HWE.

2. A sample of 1066 Chukchi individuals, the native people of eastern Siberia, has been genotyped for the MN blood group, which is determined by a locus with 2 alleles (M and N). The observed number of individuals has been: MM, 165; MN, 562; and NN, 339. Determine: (a) the allele frequencies; (b) the genotype frequencies; and (c) whether or not the population is in Hardy-Weinberg equilibrium for this locus. Reason your answer.

Please help! Please show clear explanations and methods to get to the answers so I can understand. Thank you so much in advance!

1. A person is described as a carrier for a particular genetic disease. What does this tell you about their genotype?

2. For any given gene, the principle of independent segregation predicts that each gamete produced as a result of meiosis will contain ____________________

3. A pair of alleles is said to be heterozygous when:

4. In a diploid species, cells can have up to ___ alleles of a particular gene.

5. In a cross between a homozygous dominant parent and a homozygous recessive parent, the number of phenotypic classes observed in the offspring is ______

6. For a person of genotype Xx, the genotype of their gametes may be ______________

7. In a "test cross", an individual of unknown genotype is crossed with a ___ individual to determine the unknown genotype.

8. An albino woman has a child with a phenotypically normal man with no family history of albinism (which is a rare recessive disorder). What percentage of their children are likely to be albino?

9. An individual with the dominant phenotype, but an unknown genotype, is test-crossed, and all of the offspring exhibit the dominant phenotype. The genotype of the unknown individual is ______________

10. If two heterozygous individuals for a recessive disease (carriers) have a child, what is the chance that their child will develop the disease?

11. In a monohybrid cross between two true-breeding parents that both exhibit the dominant phenotype, ___ percent of the offspring will exhibit the recessive phenotype.

12. In a particular type of tomato plant, red fruit is dominant over yellow fruit, and dwarf height is a recessive trait. If two heterozygous plants were crossed, what proportion of the offspring would show the dominant phenotype?

13. In a cross between a BbRr individual and a BBRR one, what do the following represent: BR, Br, bR, br?

14. In humans, the gene that determines whether an embryo develops as a male or a female is carried on _____________

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