Question

Serotonin, norepinephrine, and dopamine are a group of neurotransmitters collectively called monoamines. A lack of these monoamines has been linked to depression. Depression is treated with drugs that prolong the effect of these neurotransmitters either by preventing the re-uptake of the neurotransmitters, or by inhibiting the enzyme that breaks down these neurotransmitters.

Which of the following statements about neurotransmitters are true? The table lists the classifications of three antidepressants.

Antidepressant	Classification
fluoxetine	selective serotonin re-uptake inhibitor (SSRI)
phenelzine	monoamine oxidase (MAO) inhibitor
amitriptyline	tricyclic antidepressant

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Depression may be treated with monoamine agonists.

Some drug addictions are the result of dopamine agonists.

A deficiency of serotonin, norepinephrine, and dopamine is associated with depression.

MAO inhibitors are examples of monoamine antagonists.

Fluoxetine inhibits the enzyme that breaks down monoamines.

Dopamine plays a role in feelings of pleasure and pain.

Amitriptyline and fluoxetine both prevent the re-uptake of serotonin and norepinephrine.