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Which of the following is a difference between the coats of COPII- and clathrin-coated vesicles? Option A: The outer scaffold subunits of the clathrin lattice of coated vesicles overlap extensively, while those of the COPII lattice of coated vesicles do not overlap. Option B: The outer scaffold subunits of the COPII lattice of coated vesicles overlap extensively, while those of the clathrin lattice of coated vesicles do not overlap. Option C: The inner layer of adaptor proteins of COPII-coated vesicles overlap extensively, while those of clathrin-coated vesicles do not overlap. Option D: The clathrin-coated vesicles have three distinct layers, while the COPII-coated vesicles have two distinct layers

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Casey Durgan
Casey DurganLv2
28 Sep 2019

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Related questions


1. Name two similarities and two differences between thecellular processes of importing

protein into the ER and importing protein to the nucleus.

2. What proteins are directly involved in the transportation ofcargo in a clathrin-coated

vesicle?

a. Dynamin

b. Adaptins

c. Cargo receptors

d. t SNARES

3. Suppose a cell was treated with colchiine, a drug causingmicrotubule disassembly.

What would happen within the cell? Why?

Suppose there were a genetic defect in the genes that code forkinesins and dyneins.

What would happen within the cell? Why?

4. Which of the following are true about microtubules?

a. They are utilized by the disease causing bacteriaLysteria.

b. Instability in the minus-end of the microtubule is caused bythe hydrolization of GTP.

c. Centrosomes contain binding sites for microtubules composed atype of tubulin ring.

d. Cellular concentrations of tubulin are above the criticalconcentration for plus-end

polymerization.

e. Motor proteins can attach organelles to the microtubules.

5. Indicate which of the following statements are false:

a. Membrane fusion is energetically unfavorable and thusrequires ATP or similar high

energy molecule to occur

b. Clathrin is responsible for capturing specific molecules fortransport in coated vesicle

structures.

c. Receptor proteins that are incorporated into an endosome canbe retrieved back to the

membrane domain it originated from; can return to a new domainof the membrane; or

can enter the lysosome for digestion.

d. Transport vesicles occasionally bud from the trans Golginetwork to fuse with the

plasma membrane in a process called constitutive exocytosis.

e. Most components of the endocytic vesicle membrane eventuallyare returned to the

plasma membrane for reuse.

6. Match the following organelles with their function:

Organelle Bank:

a. Mitochondria

b. Endoplasmic reticulum

c. Nucleus

d. Lysosome

e. Endosome

f. Peroxisome

g. Golgi apparatus

_____ quality control of mRNA

_____ location of oxidative phosphorylation

_____ responsible for detoxifying organic molecules (livercells)

_____ houses and protects genetic material

_____ responsible for modification and sorting of proteins andlipids

_____ location of ATP synthesis

_____ responsible for sorting endocytosed materials

_____ site of degradation and digestion

_____ responsible for oxidizing toxic molecules

_____ location of lipid synthesis

_____ location of hormone synthesis (adrenal cells)

B. Which organelle(s) from the above list communicate(s) withother organelle(s)

through the use of vesicular transport? ________________

C. Which organelle(s) from the above list receive proteins madein the

cytosol?___________________

D. Through which organelle(s) must proteins pass to reach theorganelle(s) which do not

receive proteins made exclusively in thecytosol?______________

E. Entrance into which organelle(s) requires that proteinsunfold and snake through the

membrane? _________________

F. How do organelles maintain their position in the cytosol? Bespecific.

G. Give 2 advantages that eukaryotic cells gain by havingorganelles.

7. Which of the following statements are true regardingactin?

a. They are arranged in a

1) Which of the following statements about transport into the mitochondria is FALSE?

a) The signal sequence on proteins destined for the mitochondria is recognized by a receptor protein in the outer membrane of the mitochondria.

b) Proteins that are transported into the mitochondria are unfolded as they are being transported.

c) Transport of proteins into the mitochondria requires SRP and the SRP receptor.

d) After a protein is made in the cytosol it must move through two protein translocators to reach the inner mitochondrial matrix.

2.Which coat protein is involved in vesicle formation during endocytosis – vesicle forms from plasma membrane and fuses with endosomes?

a) COPI
b) COPII

c) v-SNARES d) Clathrin

3. Which of the following statements about vesicular membrane fusion is TRUE?

a) Membrane fusion does not always immediately follow vesicle docking.

b) The interactions of the v-SNAREs and t-SNAREs pull the vesicle membrane and the target organelle together so that their lipids can intermix.

c) NSF and SNAP disassemble the SNARE complex so the SNAREs can be recycled.

d) All of the above are true.

1-The following is a portion of an abstract from The Journal ofStructural Biology:
Although the ____________ of Paramecium is made up of many sets ofmore reduced stacks of
cisternae than those of many mammalian cells, the stacks inParamecium always bear a close
relationship to a transitional element of the ER from whichnon-clathrin-coated transition
vesicles arise. In QF-DE replicas two networks of filaments areclearly shown; one is in this ER-
____________ transition zone and the other is on the trans side ofthe _____________ stack. The
network associated with the trans-______________ region links anumber of vesicular elements.
The network in the transition zone spans the distance between theER and the cis-cisterna of the
______________ stack and has branches extending to the coats of theenmeshed nonclathrincoated
transition vesicles.
Which term best fills in the blank?
a. Rough endoplasmic reticulum
b. Lysosome
c. Mitochondria
d. Chloroplasts
e. Golgi (apparatus)

2. Mitochondria
a. are prevalent in aerobically respiring bacteria.
b. are capable of both synthesizing and storing starch.
c. have many integral membrane proteins across their innermembrane.
d. rely entirely upon chromosomal genes for synthesis of neededproteins.

3. Mycobacterium tuberculosis trapped in a phagosome of a host cellis able to resist
degradation by the digestive enzymes of the lysosome upon formationof the phagolysosome. With this in mind, which events occur asM. tuberculosis “exploits the
system” and enters the host cell?
a. M. tuberculosis binds to an external receptor of aclathrin-coated pit.
b. Macropinocytosis
c. Caveolae, that contain M. tuberculosis, form.
d. Pseudopods form and surround M. tuberculosis.

4. Proteus mirabilis is a bacterium. It is Gram-negative andmotile. Giardia intestinalis is a parastic, eukaryotic, motileprotist. All of the following accurately compares / contraststhesetwo organisms EXCEPT?
a. Whereas Proteus mirabilis has an outer membrane characterized byLPS, Giardia intestinalis lacks this feature.
b. Whereas the DNA of Giardia intestinalis is packaged by wrappingaround histone octamers to form nucleosomes, the DNA ofProteus mirabilis is packaged largely by supercoiling.
c. Infections caused by both Giardia intestinalis and Proteusmirabilis could be effectively treated using penicillin.
d. Whereas the flagella of Giardia intestinalis are composed ofnine pairs of microtuble doublets, the flagella of Proteusmirabilis are composed of a basal body, hook andfilament.
e. Unlike the flagella of Proteus mirabilis, the flagella ofGiardia intestinalis are membrane-bound.

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