All of the drug candidates listed below failed to make it to the market. Incidate point in the drug discovery/developement pipeline that the drug candidates probably failed.
* A cholesterol lowering drug candidate was found to lead to a serious rash in all patients tested.
* An anti-hypertension drug candidate was found to lower blood pressure in non-human primates but was only effective in humans at high doses.
* A cholesterol drug was determined to be too costly to produce in order to compete with existing drugs on the market.
* An anti-nausea drug was found to have a very short half-life due to rapid metabolism.
* An antidepressant drug candidate was found to cause severe stomach ulcers in adolescent patients.
* An analgesic drug candidates was found to have a therapeutic index of 1.2.
All of the drug candidates listed below failed to make it to the market. Incidate point in the drug discovery/developement pipeline that the drug candidates probably failed.
* A cholesterol lowering drug candidate was found to lead to a serious rash in all patients tested.
* An anti-hypertension drug candidate was found to lower blood pressure in non-human primates but was only effective in humans at high doses.
* A cholesterol drug was determined to be too costly to produce in order to compete with existing drugs on the market.
* An anti-nausea drug was found to have a very short half-life due to rapid metabolism.
* An antidepressant drug candidate was found to cause severe stomach ulcers in adolescent patients.
* An analgesic drug candidates was found to have a therapeutic index of 1.2.
