1. One of your coworkers has been taking propranolol regularly for a fast heart rate [tachycardia]. Recently she has been complaining of tiredness and a feeling that she might faint.
a. Is this effect drug related and if so, what is occurring?
b. What advice might you give your coworker and why?
2. The following question is in regards to the adrenergic system:
a. List the different types of adrenergic receptors.
b. What is the major function of each type of receptor?
c. Why is the advantage of having multiple types of receptors in this system?
3. Your elderly patient who was prescribed an anti-spasmodic drug for GI hypersensitivity is complaining of increased sensitivity to light and notices she has difficulty urinating.
a. What do you think is happening to this patient?
b. What class of drugs do you think she was most likely prescribed?
c. What class of drugs would be indicated if her condition worsened and treatment was required?
4. The following questions concern the cholinergic system. [3 pts]
a. Where are the three different cholinergic receptors located?
b. What class of drugs is needed to block each receptor?
5. Alpha- and beta-blockers are both indicated for the treatment of hypertension. Explain the difference in the mechanism of action of these two drug classes to lower blood pressure. [2 pts]
6. There are two enzymes that can break down acetylcholine. [2 pts]
a. List the two enzymes.
b. Who are they different from each other?
7. The following question is in regards to succinylcholine. [4 pts]
a. What class of drug is succinylcholine?
b. When would this drug be indicated for use?
c. Explain the difference between the phase I and phase II effects of succinylcholine.
1. One of your coworkers has been taking propranolol regularly for a fast heart rate [tachycardia]. Recently she has been complaining of tiredness and a feeling that she might faint.
a. Is this effect drug related and if so, what is occurring?
b. What advice might you give your coworker and why?
2. The following question is in regards to the adrenergic system:
a. List the different types of adrenergic receptors.
b. What is the major function of each type of receptor?
c. Why is the advantage of having multiple types of receptors in this system?
3. Your elderly patient who was prescribed an anti-spasmodic drug for GI hypersensitivity is complaining of increased sensitivity to light and notices she has difficulty urinating.
a. What do you think is happening to this patient?
b. What class of drugs do you think she was most likely prescribed?
c. What class of drugs would be indicated if her condition worsened and treatment was required?
4. The following questions concern the cholinergic system. [3 pts]
a. Where are the three different cholinergic receptors located?
b. What class of drugs is needed to block each receptor?
5. Alpha- and beta-blockers are both indicated for the treatment of hypertension. Explain the difference in the mechanism of action of these two drug classes to lower blood pressure. [2 pts]
6. There are two enzymes that can break down acetylcholine. [2 pts]
a. List the two enzymes.
b. Who are they different from each other?
7. The following question is in regards to succinylcholine. [4 pts]
a. What class of drug is succinylcholine?
b. When would this drug be indicated for use?
c. Explain the difference between the phase I and phase II effects of succinylcholine.
