PSL425H1 Lecture Notes - Polyol Pathway, Ester, Glycosidic Bond
Document Summary
Stores excess energy to be utilized later on by the brain when fasting, obligatory glucose utilization. Need system to release glucose from our body when fasting (not eating carbohydrates) storing of glucose in glycogen. Glycogen stored in muscle (meat) is important for the muscle to provide muscle with glucose to be broken down when exercising. Glycogen in liver (not much) important for quick adaptation of glucose to exercise, to avoid hyperglycemia; important for the quick regulation of plasma glucose. Glycosidic bond (interior) formed by 2 oh of glucose (decondensation) 1-4 and 1-6 bonds. Diff enzymes affecting synthesis vs. breakdown for regulation. Glycogen synthesis has to occur at time of glucose elevation, stimulated by glucose itself and by insulin. As soon as glucose is phosphorylated, it doesn"t leave the cell (hormone intermediate of fixing glucose inside cell then handled in diff ways) Synthesis starts from glucose 1-phosphate (isomerization from g6p) by pglucomutase.
