PSL300H1 Lecture Notes - Cardiac Muscle, Calmodulin, Skeletal Muscle
Document Summary
Because when the person dies they no longer generate atp, one last power stroke of myosin (?) makes the muscle stiff or contracted forever. After a while, protein that makes up the muscle, breaks down so the body doesn"t stay like that forever. So you can approximate the time of death. N. sl at the t tubule, you"ll find dhp (which is an l type calcium channel). With the arrival of the ap, there occurs a conformation change and therefore calcium is released from the sarcoplasmic reticulum. N. sl- with calcium, the actin binding sites are open, the crossbridge cycle we"ve seen occurs. N. sl- to terminate the contraction we have to remove the calcium, we"ll use a calcium pump to pump ca back into the sarcoplasmic reticulum. This is a very fast process for skeletal muscle not for cardiac or soft tissue muscles because the source of calcium is right there in the sarcoplasmic reticulum.
