BIOL 2P03 Lecture Notes - Lecture 12: Innate Immune System, Adaptive Immune System, Screencast
20 Apr 2017
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Document Summary
Immune system: the immune system consists of a collection of specialized tissues, cells, signaling molecules and anti- microbial agents that protect the body from invading micro-organisms and promote tissue repair. Monocytes: circulate in the bloodstream, enter tissues throughout the body where they subsequently differentiate into macrophages. Macrophages: professional antigen presenting cells, digest phagocytosed materials and attach them to specialized surface receptors (mhc class. Ii receptors: mhc class ii receptors bound to microbial antigens are then presented to t cells to activate the adaptive immune system. Neutrophils: most abundant white blood cell, circulate throughout the blood and can be recruited to sites of injury or infection, similar to macrophages, neutrophils also engulf foreign material via phagocytosis and destroy it, and they also release cytokines. Eosinophils: particularly important during allergic reactions and parasitic diseases, can destroy parasites. Basophils and mast cells: release mediators that promote inflammation and allergic responses.
