NROC69H3 Lecture Notes - Lecture 5: Resting Potential, Disinhibition, Executive Functions
Document Summary
Lecture outline: anatomy and function of basal ganglia, multifaceted functions, basal ganglia is not only associated with motor function, it is one of the most oldest structures, neural circuitry, afferent input to striatal principal neurons. Intrinsic properties of msn, interneurons: medium spiny neurons (msn, dopaminergic input, patch / matrix pathways, output from the basal ganglia, direct / indirect pathways, dopamine action and function. Basal ganglia components: four sets of nuclei, striatum, caudate, putamen, globus pallidus, internal gp, external gp, subthalamic nucleus, stn, substantia nigra (sn, pars compacta (snc, source of dopamine neurons, pars reticulata (snr, source of output of bg. Striatum and subdivisions: ventral striatum, nucleus accumbens, aka ventral striatum, dorsal striatum, putamen, caudate. Cross species homology: bg fundamentally important structure, not directly connected to any motor / sensory structures in the brain. Integrate and connect information regarding emotions into meaningful behaviors.
