BCH210H1 Lecture Notes - Leucine, Lipid Bilayer, Electron Diffraction

• School: UTSG
• Department: Biochemistry
• Course: BCH210H1
• Professor: Roman Melnyk

Document Summary

Selectively permeable (no nutrition in, no o2 in, no waste out all permeable not good. Compartmentalize genetic material so it stays distinct. Review structure and properties of fatty acids. Review structure and properties of the most common lipid found in membranes. Describe the role of lipids in health and disease: glycerophospholipids, sphingolipids, cholesterol. Lecture 1 overview lipid structure and properties. Fatty acids is a much more diverse family. Alkane adopts lowest energy form based on steric. Physiological ph most acids are deprotonated . Extended conformation = zigzag: low in water and high in non-polar solvents, contain both polar and non-polar groups, hydrophobic effect and van der waals makes them more polar. 4 ways to name a fatty acid but only talk about 3: symbol, [#c]:[# of double bonds, 18:0, systematic name, octadecanoic acid. Mono-unsaturated fatty acids: common name, steric acid. Double bonds almost always in cis conformation. Common name: 18:1, 9-octadecenoic acid, oleic acid, 18:2, 9,12-octadecadienoic acid, linoleic acid.