PHAR 100 Lecture Notes - Atherosclerosis, Headache, Xanthine

• School: Queen's University
• Department: Pharmacology and Toxicology
• Course: PHAR 100
• Professor: Hisham Elbatarny

Document Summary

Energy drinks fortified with extra-large amounts of caffeine: rockstar: 16 oz, 160 mg caffeine, red bull: 8. 3 oz, 80 mg caffeine. Caffeine: introduction: member of a family of drugs called methylxanthines naturally occurring in a number of species of plants: found in coffee, tea and chocolate first isolated from coffee by german chemist: called kaffeebase. History of tea sold commercially in china by 780 ad. 1630s: dutch started shipping tea to europe, germany and france became a major export from england in 1760: 3rd largest export from britain to the colonies tea smuggling: tea tax on all tea imported into britain. Route of administration: oral rapidly and completely absorbed plasma levels peak about 90 min after consumption freely crosses the placenta. Cns: cerebral cortex: increased mental performance, decreased drowsiness and fatigue, enhanced motor activity, medulla, stimulation of respiratory and vasomotor centres, increased respiration and heart rate.