PHAR 100 Lecture Notes - Nicotiana Tabacum, Peripheral Nervous System, Asubpeeschoseewagong First Nation

• School: Queen's University
• Department: Pharmacology and Toxicology
• Course: PHAR 100
• Professor: Hisham Elbatarny

Document Summary

Acute toxicity single exposure often large dose: e. g. chemical spill. Chronic toxicity repeated exposure prolonged time period small doses: e. g. eating contaminated food. Acute toxicity usually more obvious effects acute effects often different from chronic effects: e. g. aflatoxin b1 (common food contaminant, acute: liver necrosis, liver failure, death, chronic: liver cancer. 1273 first antipollution law early 20th century automobiles. 1952 killer smog in london, england: dense fog + smoke, so2, particulates, 4,000 deaths, bronchitis, pneumonia, etc, demonstrated the lethality of air pollution. Major air pollutants gaseous: carbon monoxide (co), hydrocarbons, hydrogen sulfide, nitrogen oxides, ozone, sulfur oxides, carbon dioxide (co2) particulate matter: mixture of tiny particles that are composed of organic, inorganic and biological materials; solids, liquid droplets. Natural volcanoes forest and prairie fires dust storms trees, plants. Human-made anthropogenic: of, relating to, or resulting from the influence of human beings on nature three main sources.