BIOL201 Study Guide - Wilson Disease Protein, Cytogenetics, Telomerase Reverse Transcriptase

• School: University of Alberta
• Department: Biology (Biological Sciences)
• Course: BIOL201
• Professor: Michael Harrington

Document Summary

Biology 207 a1 - fall 2011 - midterm one. Question 1 people with wilson disease can"t metabolise copper. Left untreated this leads to liver and neural damage: the gene involved, atp7b, is at 13q14. Describe this cytogenetic location. (2 marks: some people with this disease have a asn915ser mutation. Provide one possible example of what the dna and mrna sequences might be in healthy and in affected people. Include the polarity (3"--5") of all of the nucleic acids. (4 marks) Question 2 recall that the human telomerase enzyme is made of a protein called tert and an rna called terc. The template region of the human terc rna is: Question 3 within a gene a cytosine (c) deaminates and become a uracil (u). Chromosome replication in an e. coli cell begins at the. _____________________________________________________ on the chromosome and ends when the. Biology 207 a1 - fall 2011 - midterm one - id _________________