BIO130H1 Chapter Notes -Alpha Helix, Coiled Coil, Nucleoside Triphosphate

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BIO130H1 Full Course Notes
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The self-assembly and dynamic structure of cytoskeleton filaments. 3 types of cytoskeletal filaments: intermediate filaments: provides mechanical strength, microtubules: positions of membrane enclosed organelles and direct intracellular transport, actin: determines shape of cell and required for cell locomotion. Need accessory protein to link the filaments to cell components. Accessory proteins are essential to control the assembly of the cytoskeleton and specific locations; this includes motor proteins convert atp to adp and p to move organelles along a filaments. Microtubules are found at the center and radiate outwards; so it can form a mitotic spindle during cell division. Can also form cillia and flagella on the surface of a cell. Actin filaments: underlie plasma membrane of animal cells. Provides strength and shape of to its thin lipid bilayer. Actin based contractile ring: assembles to divide cell into two; allows for more stability. Microvilli: increases the surface area for absorption.

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