BIO130H1 Lecture Notes - Lecture 7: Helicase, Consensus Sequence, Regulatory Sequence
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BIO130H1 Full Course Notes
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The entire nucleic acid sequence (usually dna) that is necessary for the synthesis of a protein (and its variants) or rna. Genes are segments of dna that are transcribed into rna. Two types of genes transcribed: the resulting rna encodes a protein, the resulting rna functions as rna. Rna polymerase does not need a primer to initiate( ) chain synthesis. It can start by recognizing a complementary strand of dna. *generation of rna transcript: template: single stranded dna, rna (the rntp) linked by phosphodiester bonds, dna-rna hybrid held together by base pairing (recording 10) Sigma factor binds to promoter (specific sequences on dna), the regions is where the rna polymerase is going to start the transcription. While sigma factor dissociate from rna polymerase, rna polymerase goes through abortive steps (rna polymerase moves down the dna strands several times). +localized unwinding of dna by sigma factor, providing access to the template.
