BIOL 300- Final Exam Guide - Comprehensive Notes for the exam ( 155 pages long!)

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Prokaryotic genome: plasmid: circular extrachromosomal dna molecule capable of autonomous replication, the dna sequences of the extra-chromosomal plasmids of bacteria and certain lower eukaryotes (ex: yeast) are typically included in the genomes of these organisms. Common structures of nucleotides: nucleotides are composed of organic base like adenosine, a sugar molecule (ribose or deoxyribose) and a phosphate, nucleoside is when the phosphate is absent, rna is composed of ribose. Ribose has a hydroxyl group on both the 3" and 2" position. Space-filling model of the dna double helix: anti-parallel double-stranded helix (makes dna more stable, base-pairing stabilizes helix, sugar-phosphate backbones are outside, major and minor grooves are formed, which are recognized by sequence-specific. Dna binding proteins: the bases in the double helix are accessible from the major and minor grooves of. B-dna: protein interactions can bend dna, tata-box-binding protein can bind the dna.

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