BIOLOGY 2B03 Study Guide - Cell Cycle, Leucine, Histone H1


Department
Biology
Course Code
BIOLOGY 2B03
Professor
Dr, Da Silva, Dr.K.Dej

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Module 9: Cell cycle regulation
Lecture 1: Cyclin-dependent kinases and E3 ligases
1

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Objectives
Outline the phases of the cell cycle: G1-S-G2-M
phase.
Identify the functions of key cell cycle regulators:
kinases and E3 ubi
q
uitin li
g
ases. Describe their
qg
target proteins.
Examine experiments that identified the activities
Examine experiments that identified the activities
of key cell cycle regulators.
2

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Cell cycle phases
3
4 phases (G1, S, G2 and M,mitosis)
G0= no division occurs
G1= cell is actively
growing,engaged
in gene expression
and the synthesis
of new proteins
S= replicates the genome
failure in cell cycle can lead to apoptosis or proliferation
Gap 2=G2
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