ENH 122 Study Guide - Midterm Guide: Achlorhydria, Serotype, Myalgia
Document Summary
Sudden onset; profuse watery stools (enterotoxin affecting small intestine), Untreated: dehydration, acidosis, circulatory collapse, hypoglycemia in children, renal failure. Case fatality can exceed 50% (less than 1% with proper rehydration) Signs may be non-specific w/ fever, chills, mlaise, myalgia, nausea, prostration, sore throat & headache. Plague: lymphadenitis = infection of the lymph nodes causing buboes. Ingestion of an infective dose of contaminated food or water. Water usually contaminated by feces of infected individuals. & food, poor hygiene, poor sanitation & crowded living conditions. Developing countries, peri-urban slums were basic urban infrastructure is missing. As long as stools are positive, few days after recovery carrier state could persist for several months. Gastric achlorhydria increases risk of illness, breast fed infants are protected. Occurs more in people with blood group o. Most in areas where wild rodents are a common pest like. Rodents are the amplifying host (source of infection) but fleas remain the vectors of the disease;