BPK 105 Study Guide - Final Guide: Pancreas, Vagus Nerve, Cholecystokinin

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browncricket987

27 Apr 2018

School

Simon Fraser University

Department

Biomedical Physio & Kines

Course

BPK 105

Professor

Ryan Dill

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Module 11 - Review Questions - Part 4

7. Describe the control of release and function of each of the secretions from the

exocrine pancreas. [7 marks]

- The exocrine part of the pancreas is a compound acinar gland.

- The acini produce digestive enzymes.

- The exocrine secretions of the pancreas include bicarbonate ions (HCO3−), which

neutralize the acidic chyme that enters the small intestine from the stomach. The

increased pH resulting from the secretion of HCO3− stops pepsin digestion but provides

the proper environment for the function of pancreatic enzymes.

- Pancreatic enzymes are also present in the exocrine secretions and are important in

digesting all major classes of food (see table 16.1). Without the enzymes produced by

the pancreas, lipids, proteins, and carbohydrates cannot be adequately digested.

- The major proteolytic (protein-digesting) enzymes are trypsin, chymotrypsin, and

carboxypeptidase. These enzymes continue the protein digestion that started in the

stomach, and pancreatic amylase continues the polysaccharide digestion that began in

the oral cavity.

- The pancreatic enzymes also include lipase, a lipid-digesting enzyme, and nucleases,

which are enzymes that degrade DNA and RNA to their component nucleotides.

- The exocrine secretory activity of the pancreas is controlled by both hormonal and neural

mechanisms (figure 16.20; see table 16.2).

- Secretin initiates the release of a watery pancreatic solution that contains a large amount

of HCO3−.

- The primary stimulus for secretin release is the presence of acidic chyme in the

duodenum. Cholecystokinin stimulates the pancreas to release an enzyme-rich solution.

- The primary stimulus for cholecystokinin release is the presence of fatty acids and amino

acids in the duodenum. In turn, enzymes secreted by the pancreas act to digest these

fatty acids and amino acids.

- Parasympathetic stimulation through the vagus nerves also stimulates the secretion of

pancreatic juices rich in pancreatic enzymes. Sympathetic action potentials inhibit

pancreatic secretion.

8. Distinguish between the processes of digestion and absorption through definition and

description. Where in the gastrointestinal system do they generally take place? [4 marks]

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Document Summary

Module 11 - review questions - part 4: describe the control of release and function of each of the secretions from the exocrine pancreas. The exocrine part of the pancreas is a compound acinar gland. The exocrine secretions of the pancreas include bicarbonate ions (hco3 ), which neutralize the acidic chyme that enters the small intestine from the stomach. The increased ph resulting from the secretion of hco3 stops pepsin digestion but provides the proper environment for the function of pancreatic enzymes. Pancreatic enzymes are also present in the exocrine secretions and are important in digesting all major classes of food (see table 16. 1). Without the enzymes produced by the pancreas, lipids, proteins, and carbohydrates cannot be adequately digested. The major proteolytic (protein-digesting) enzymes are trypsin, chymotrypsin, and carboxypeptidase. These enzymes continue the protein digestion that started in the stomach, and pancreatic amylase continues the polysaccharide digestion that began in the oral cavity.

Related Questions

1. Food passing into the small intestines is very acidic from the hydrochloric acid released by the lining of the stomach and mixed in by churning. The pH of the stomach is about 2 whereas the pH of the small intestines is about 8. A buffer, bicarbonate, is released by the pancreas and used to convert the pH 2 chyme solutions (food) to a pH 8. Explain the importance of the buffer to the continued digestion of your food.

2. Your enzymes have specificity. With this in mind, explain why you need no less than ten different enzymes working on digestion in your small intestines.

3. In a eukaryotic cell there is one nucleus and several mitochondria. Both of these organelles are surrounded by a membrane and contain DNA. With your knowledge of a minimal cell, the cell theory and the endosymbiotic hypothesis, explain whether or not they fit the criteria to be considered a cell and support your answer.

4. Your pancreas cells produce many digestive enzymes necessary for the final digestive processes in your small intestines, including pancreatic amylase to complete the digestion the starches in your food. The pancreatic amylase is secreted from the cells of the pancreas and is carried to the small intestine in the common bile duct. Describe the pancreas cellâs processes that it must go through from production to secretion of this enzyme (amylase).

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The digestion process begins at the mouth. Food enters and then accessory digestive organs like the tongue, teeth, and salivary glands break down the substance. It then travels through the pharynx and esophagus into the stomach, where the stomach acid further breaks down the food (UXL Complete Health Resource). After that, the food travels through the small and large intestines where a majority of its nutrients are absorbed. The waste then exits through the end of the large intestine which is made up of the rectum and anus. After the teeth assist in chewing, food rolls over the tongue and reaches stomach through the esophagus within 8 seconds. General Tsoâs Chicken and Rice consist of carbohydrates, fats and proteins. However, carbohydrates are digested easily than the fats and proteins. After broken down in the stomach, most of the nutrients are absorbed from the small intestine, and it takes 6 to 8 hours to pass through small intestine. The remaining unabsorbed material, âmoves very slowly through the large intestine where the final absorption of water and other nutrients take placeâ (UXL Complete Health Resource). The parasympathetic nervous system encourages the food to move through the digestive tract and motivates digestion process. The sympathetic nervous system works against the parasympathetic nervous system by decreasing the contraction and relaxation of the digestive tract (Taylor). Mouth produces saliva, which contains amylase. Amylase is key in digesting carbohydrates. The stomach produces hydrochloric acid, pepsinogen, intrinsic factor, and mucus (Taylor). Hydrochloric acid kills the bacteria and other organisms that enter the stomach, and then continues to activate pepsinogen. Pepsinogen then changes into pepsin, which digests protein peptides. The pancreas produces trypsin, chymotrypsin, carboxypeptidases, lipases, and phospholipases. Trypsin, chymotrypsin, and carboxypeptidases digest proteins, whereas lipases, phospholipases digest lipid molecules. Small intestine produces lactase, sucrase, maltase, lipases, and peptidases. Lactase, sucrase, and maltase digest carbohydrates (UXL Complete Health Resource). Saliva glands, pancreas, liver, and gallbladder are the accessory organs of the digestive process. Saliva glands produce mucus and amylase which digests starch into simple sugars and binds food particles together, while lubricating the palette when one swallows. The pancreas produces amylase, lipases, and proteinases etc. These digestive juices are responsible for breaking down carbohydrates, proteins, and fats. The liver is the largest gland in the body, âIt produces bile salts to emulsify lipids. It detoxifies metabolic end products to protect the bodyâ (UXL Complete Health Resource). Gallbladder stores bile juice. The chicken in the General Tsoâs contains proteins. Proteins cannot be digested in mouth. However, the mouth can physically digest chicken into smaller pieces. These partially digested chicken pieces travel to stomach, where it is digested by pepsin. The pancreas produces trypsin, chymotrypsin, carboxypeptidases, lipases, and phospholipases (UXL Complete Health Resource). The chicken is then digested by trypsin, chymotrypsin, and carboxypeptidases in the duodenum of the small intestine. After the complete digestion, the chickenâs proteins change into amino acids, which are then absorbed into blood. The rice of the General Tsoâs is a carbohydrate. Carbohydrates are partially digested inside the mouth by amylase. The rest of the rice travels to the stomach where it is digested by pancreatic juices and enzymes that are produced by small intestine. The digestion of the rice produces monosaccharides that absorb into the blood stream. The left over, and undigested parts of the chicken and rice that are useless to the body are excreted by large intestine through rectum.

1) Based on your finding in the Module 3 Report, begin the Module 4 Report by identifying which metabolites are being absorbed and specifically which vessels of the cardiovascular or lymphatic system are the initial vessel of transport from the digestive system. 2) From the point that the specific metabolites are absorbed from the GI tract, trace the path of the resulting metabolites to the following locations in the body for incorporation into the body structure: Metabolites of protein for use in the Gastrocnemius muscle for muscle maintenance. Metabolites of the carbohydrates for energy to contract the cardiac muscle cells. Metabolites of fat to incorporate into the myelin sheaths of the Schwann cells of the Trigeminal nerve that innervates the Masseter muscle. Water for incorporation into the synovial fluid of the hip joint. Iron for incorporation into red blood cells in the bone marrow of the sternum.

maroonguinea-pig686

Food that we consume is composed of very complex molecules. During the digestive process these compounds are broken down into smaller and smaller subunits in preparation for use by the body as building blocks needed for the many components of the human body. The digestion process begins at the mouth. Food enters and then accessory digestive organs like the tongue, teeth, and salivary glands break down the substance. It then travels through the pharynx and esophagus into the stomach, where the stomach acid further breaks down the food (UXL Complete Health Resource). After that, the food travels through the small and large intestines where a majority of its nutrients are absorbed. The waste then exits through the end of the large intestine which is made up of the rectum and anus. After the teeth assist in chewing, food rolls over the tongue and reaches stomach through the esophagus within 8 seconds. General Tsoâs Chicken and Rice consist of carbohydrates, fats and proteins. However, carbohydrates are digested easily than the fats and proteins. After broken down in the stomach, most of the nutrients are absorbed from the small intestine, and it takes 6 to 8 hours to pass through small intestine. The remaining unabsorbed material, âmoves very slowly through the large intestine where the final absorption of water and other nutrients take placeâ (UXL Complete Health Resource). The parasympathetic nervous system encourages the food to move through the digestive tract and motivates digestion process. The sympathetic nervous system works against the parasympathetic nervous system by decreasing the contraction and relaxation of the digestive tract (Taylor). Mouth produces saliva, which contains amylase. Amylase is key in digesting carbohydrates. The stomach produces hydrochloric acid, pepsinogen, intrinsic factor, and mucus (Taylor). Hydrochloric acid kills the bacteria and other organisms that enter the stomach, and then continues to activate pepsinogen. Pepsinogen then changes into pepsin, which digests protein peptides. The pancreas produces trypsin, chymotrypsin, carboxypeptidases, lipases, and phospholipases. Trypsin, chymotrypsin, and carboxypeptidases digest proteins, whereas lipases, phospholipases digest lipid molecules. Small intestine produces lactase, sucrase, maltase, lipases, and peptidases. Lactase, sucrase, and maltase digest carbohydrates (UXL Complete Health Resource). Saliva glands, pancreas, liver, and gallbladder are the accessory organs of the digestive process. Saliva glands produce mucus and amylase which digests starch into simple sugars and binds food particles together, while lubricating the palette when one swallows. The pancreas produces amylase, lipases, and proteinases etc. These digestive juices are responsible for breaking down carbohydrates, proteins, and fats. The liver is the largest gland in the body, âIt produces bile salts to emulsify lipids. It detoxifies metabolic end products to protect the bodyâ (UXL Complete Health Resource). Gallbladder stores bile juice. The chicken in the General Tsoâs contains proteins. Proteins cannot be digested in mouth. However, the mouth can physically digest chicken into smaller pieces. These partially digested chicken pieces travel to stomach, where it is digested by pepsin. The pancreas produces trypsin, chymotrypsin, carboxypeptidases, lipases, and phospholipases (UXL Complete Health Resource). The chicken is then digested by trypsin, chymotrypsin, and carboxypeptidases in the duodenum of the small intestine. After the complete digestion, the chickenâs proteins change into amino acids, which are then absorbed into blood. The rice of the General Tsoâs is a carbohydrate. Carbohydrates are partially digested inside the mouth by amylase. The rest of the rice travels to the stomach where it is digested by pancreatic juices and enzymes that are produced by small intestine. The digestion of the rice produces monosaccharides that absorb into the blood stream. The left over, and undigested parts of the chicken and rice that are useless to the body are excreted by large intestine through rectum. 1) Based on your finding in the Module 3 Report, begin the Module 4 Report by identifying which metabolites are being absorbed and specifically which vessels of the cardiovascular or lymphatic system are the initial vessel of transport from the digestive system. 2) From the point that the specific metabolites are absorbed from the GI tract, trace the path of the resulting metabolites to the following locations in the body for incorporation into the body structure: Metabolites of protein for use in the Gastrocnemius muscle for muscle maintenance. Metabolites of the carbohydrates for energy to contract the cardiac muscle cells. Metabolites of fat to incorporate into the myelin sheaths of the Schwann cells of the Trigeminal nerve that innervates the Masseter muscle. Water for incorporation into the synovial fluid of the hip joint. Iron for incorporation into red blood cells in the bone marrow of the sternum.

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BPK 105 Study Guide - Final Guide: Pancreas, Vagus Nerve, Cholecystokinin

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