1) What does the name amphetamine refers to? What kind of drug is amphetamine?
Methamphetamine? What’s special about this one and what structural make it like
that? A Crystal meth? What’s special about this one?
2) What is Benzedrine?
3) What are the effects of amphetamines? What is it similar to?
4) Sources: what is the different btw this and the cocaine source? What was it
originally synthesized for? Why did they stop? What has it been used for? What is
narcolepsy? Can amphetamine be used to treat it?
5) What transporters (2 of them) does it interact with? Why these two?
6) Give reason why methamphetamine is becoming the choice of drug now? (Hint
mention onset, effects area) when can it be smoked?
7) Methamphetamine synthesis: which country does it come from? What is
pseudoephedrine? For every 1 Kg of product, how much waste do you produce
(hint: 1:5 ratio). What is the shake and bake/one pot method? Why do people use
this one? What are the dangers?
8) Pattern of use: in what way can it be used? How do the effect and the dose
administered frequency compare to cocaine? What happen to the NT level and
what does this lead to? To have the same effect what do you need to do with just
9) Meth vs. Cocaine: how do the High you get and the amount that remains in your
brain compare btw the two?
10)Meth vs. Cocaine: How about the dopamine level (how much increase in percent
do you get in the dopamine level as compare to normal? And what exactly is the
reason for this extreme percentage?
11) Metabolism: what is the major enzyme in the liver that does it? What are the two
major products that are formed from amphetamines? What is the effect of these
12)Metabolism methamphetamine: what are the metabolites that are formed. T/F it
has the same metabolites formed as amphetamine. T/F 20% Caucasians are
deficient in CYP2D6 and thus give them problems.
13)Mechanism of action: what does it do? How is this similar to cocaine? Give
treason of how it is it different from cocaine?
14) Mechanism: how does the mechanism of cocaine and amphetamine