PHYSL212 Study Guide - Memory T Cell, Eosinophil, Neutrophil

• School: University of Alberta
• Department: Physiology
• Course: PHYSL212
• Professor: Saswati Das

Document Summary

Role of white blood cells in immune defense. Bone narrow (stem cells (cid:0) wbc precursors) (cid:0) thymus (cid:0) blood vessels (cid:0) tissues. Role of wbcs (mainly granulocytes and monocytes/macrophages) Roles of the immune system: appropriate ( good ) Defense against foreign invaders (e. g. : bacteria, viruses) Removal of own old damaged abnormal cells. Inflammation is an example of an innate response to infection of injury. Increased movement of wbcs (neutrophils and monocytes) into infected area. Accumulation of leukocytes or wbcs in the affected tissue. Tethering and rolling of wbcs inside blood vessel. Arrest/firm attachment of wbcs to endothelial cells. Ability of wbcs to move along a concentration gradient (low to high) in response to chemical factors (chemotactic factors: chemotactic factors include: How to phagocytes recognize bacteria: by using prr (pattern recognition receptors or toll-like receptors, opsonins speed up the process of phagocytosis.