PHYSL212 Study Guide - Blood Transfusion, Antibody, Hemolysis

• School: University of Alberta
• Department: Physiology
• Course: PHYSL212
• Professor: Saswati Das

Document Summary

A gene (cid:0) a-enzyme (cid:0) a group. B gene (cid:0) b-enzyme (cid:0) b group. A and b genes (cid:0) a+b enzyme (cid:0) ab group. O gene (cid:0) no functional enzyme (cid:0) o group. Antibodies of the abo system, usually of the igm class, are classified as naturally occurring antibodies. D gene (d) (cid:0) d antigen (rhesus pos) Deletion of the d gene (d) (cid:0) no d antigen (rhesus neg) Antigens of the rhesus system are proteins which form an integral part of the rbc membrane. Antigens of the antibodies of the rhesus system. Antibodies of the rhesus system are of the igg class. Only rh- people can produce these antibodies after exposure to the d antigen. Agglutination or clumping: the clumping of cells such as bacteria or red blood cells in the presence of an antibody. The antibody or other molecule binds multiple particles and joins them, creating a large complex.