BIOL308 Study Guide - Protein Synthesis Inhibitor, Rna Editing, Ferritin
13 Jun 2013
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Document Summary
List and briefly explain different mechanisms of post-transcriptional control of gene expression (think about examples): localization of mrna to specific regions: mrna is positioned close to the sites where the proteins coded by that particular mrna are required. This is done with the help of the cytoskeleton (microtubules, microfilaments and actin filaments) which provides the pathway for the transport of the mrna. : axis formation during development (bicoid mrna is localized in the anterior part of the egg) & beta-actin mrna localization in the leading edge of fibroblasts: rna editing: they are alterations in the sequence of the mrna. In protozoan mitochondria: addition or deletion of u residues. In mammals: single-nucleotide site-specific editing (a to i) and c to u. : synthesis os the two forms of apolipoprotein-b proteins (apob) Caa (glutamine) is changed uaa (stop codon) causing an early termination and formation of apo-b48 in intestines.
