ANP 1105 Midterm: Neurons 2 (All you need to know for midterms)

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Special features of neurons that set them apart from most other cells in body (2. 2. 1. 1/2. 2. 1. 2) Funcional regions (plasma membrane are very important in all regions) Large, spherical nucleus + granular cytoplasm -> biosyntheic centre. Extensive rer + ribosome clusters (nissl bodies); elaborate golgi and lots of mitochondria. Branches at the end (~10,000 telodendria) which end in axonal terminals. Same organelles as cell body, but no nissl bodies, axons quickly degenerate if cut. Elaborate cytoskeleton in axon to move material to & from: Na+/k+ atpase in terms of its role in maintaining the rmp of a neuron (2. 2. 2. 2) Negaive because inside of cell is ve compared to outside. At rest: membrane somewhat permeable to k+ but only very slightly permeable to na+ Disinguish between passive (leakage) and acive (gated) channels (2. 2. 2. 4) Channels ion-speciic: channels open-> ions move in response to electrochemical gradients. Channels on axons open & close in response to local currents (graded potenials)