BCH 3120 Study Guide - Quiz Guide: Stratum Granulosum, Stratum Spinosum, Stratum Lucidum

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Terms: largest organ of the body, related terms. Dermal (related to or e ecting the skin, especially dermis) Dermatosis(any disease of the skin, particularly one involving in ammation) Desquamation(removal of the outer layer of the epidermis by scaling: pre xes: derm-, derma-, dermato. Structure of the skin: the total skin surface area (70kg bodyweight): 1. 8m2, every 1cm2 of human skin approximately contains: 3 million cells: skin surface: ph = 5. 5 (acid mantle, epidermis layer (200 m thick, 800 m thick on, dermis layer (1-5mm thick) palms/soles, 60 m on eyelid) Composed mainly of keratinocytes [which synthesize keratin (insoluble protein) and lipids], melanocytes and dendritic (langerhans) cells. Contains blood vessels, nerves and appendages (sweat glands, sebaceous glands, hair follicles) Maintains sink condition (due to its vasculature: subcutaneous tissue layer. Target regions: skin surface camou age or cosmetic preparations protective lms barriers, sunscreens antifungal and antibacterial preparations . Absorption motion sickness scopolamine: angina nitroglycerin, hypertension clonidine, smoking cessation nicotine.

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