BIO 1140 Study Guide - Final Guide: Tata Box, Start Codon, Rna Splicing
10 Sep 2016
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Document Summary
Initiation rna polymerase binds to the dna at a specific site (promoter) and unwinds the dna to reveal the gene of interest. In the promoter region belongs the tata box which is the binding site of histones and is involved in the process of transcription by rna polymerase. Elongation builds mrna transcript using the dna as an original template from the start codon. Termination after passing the end of the gene, rna polymerase recognizes the stop codon and mrna is then released where it will exit the nucleus: rna processing. Capping - at the end of transcription, the 5" end of the rna transcript contains a free triphosphate group since it was the first nucleotide in the chain; a cap replaces the triphosphate group. The main function of the 5" cap is to regulate the nuclear export, prevent being digested by enzymes from the 5" end, promotes translation, and promotes intron splicing.
