BPS4101- Final Exam Guide - Comprehensive Notes for the exam ( 65 pages long!)

• School: University of Ottawa
• Department: Biopharmaceutical sciences
• Course: BPS 4101
• Professor: Josee Coutu

Document Summary

Split into a set of linear dna molecules (applies to all eukaryotes studied to date) # of chromosomes is variable between eukaryotes: eukaryotic organisms are very diverse, dear = 6 chr; yeast = 16 chr; fruit fly = 8 chr, can"t use chromosome number to determine complexity. # chromosomes are not linked to genomic size: bigger chromosomes can carry more genetic info! C-value paradox: c-value: references dna content of cells. Paradox: amount of dna in a haploid cell is not related to the evolutionary complexity of the organism: human cells have 5x less dna than an onion, but we are more complex. Introns (gene continuity: non-coding dna, repetitive elements in the dna, gene density (intergenic regions, regulatory elements, pseudogenes, multiple copies. C-value enigma: more reflective of the current state of genomics research, deals with issue in variable amount of non-coding dna between diff eukaryotes, c-value tends to correlate with features of cell/organism: cell size.