GRT 2111 Study Guide - Midterm Guide: Cell Culture, Endothelium, Pulmonary Artery
9 Apr 2018
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Accumulation of normal injury due to continued use. Our bodies repair themselves, replace lost cells & damaged proteins, make new mitochondria and molecules, fix dna, etc (cid:862)wear a(cid:374)d tear(cid:863) theories assu(cid:373)e that orga(cid:374)is(cid:373)s (cid:449)ear out i(cid:374) the sa(cid:373)e (cid:449)ay as (cid:373)a(cid:272)hines. Our bodies are very good at repairing themselves. All cells are exposed to free radical damage, but only certain cells age. Mutations occur in cells (soma) due to repeated replication, exposure to toxins, radiation or ultraviolet light. The body can correct/destroy mutations, but not all of them, and eventually the mutated cells accumulate. Aging is caused by cumulative errors in dna/rna. Free radicals are chemical byproducts of normal cell metabolism involving oxygen. Dealing with free radicals cells need to make free radicals in order to produce atp, and they produce more free radicals as they get older free radicals need to be kept away from dna & critical cell proteins.
