HSS 1100 Study Guide - Final Guide: Ampicillin, Mucous Membrane, Gram Staining
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HSS 1100 Full Course Notes
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Gram positive often nosocomial (stitch accesses, infected wounds, ect. ) opportunistic when on skin surface and brought inside by needle or blade. N cytotoxin - cell damage/ death haemolysins - destroys blood cells enterotoxins - damage gi tract exfoliative - skin sluffs off (scaldedhhh skin syndrome) B hemolytic can completely destroy blood, a hemolytic can partially, g hemolytic cannot. Produces many toxins with speci c receptors (listed in symptoms) Produces coagulase (coagulation of brin) and beta-lactamase (destroys penicillin) enzymes. Normal part of skin and mucous membrane ora. Separated into groups based on haemolytic properties (alpha/ beta), carbohydrate c antigen, and m protein. Streptococci pyogenes (group a) congenital - found in the vaginas of healthy women. Y acute tonsillitis, heart disease (antibodies too similar to one in heart wall), impetigo, cellulitis, fever, septicaemia culprit for necrotizing fasciitis. Neonatal infections - early septicaemeia, resp. distress or shock, high fatality rate. Enzymes (hyaluronidase helps spreading of bacteria by breaking down ct)