HSS 1100 Lecture Notes - Lecture 4: Lancefield Grouping, Streptococcal Pharyngitis, Opportunistic Infection
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Hss1100 lecture #4 gram positive/negative cocci. Streptococci: arranged in pairs or forming chains. Streptos greek work for twisted: subdivided into groups based on, haemolytic properties (alpha, beta, carbohydrate c antigen (lancefield classification, m-protein, divides beta-haemolytic, mostly group a. Streptococcus pyogenes: group a, beta-hemolytic, s. pyogenes causes, acute tonsillitis (strep throat) can lead to rheumatic heart disease, fever and septicaemia. Streptococcus agalactiae: group b, found in vagina of healthy women (can cause neonatal infections, early septicaemia, respiratory distress or shock at birth, high fatality rate (serious, delayed meningitic form, 1-12 weeks post- partum, sequelae. 90 distinct capsular serotypes: can cause found in naso-pharynx of healthy individuals lobar pneumonia, meningitis, prevention strategies (elderly, alcoholics, crowded living, vaccination) N. meningitdis: gram negative diplococci, laboratory isolation using cholate agar, use selective media (ex. Only infects human!: usually children or those living in croweded living quarters, occasional epidemics.