MIC 4124 Study Guide - Midterm Guide: Opsonin, Adaptive Immune System, Leukotriene

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Invasion by and multiplication of pathogenic microorganisms in a body part or tissue. The state produced by the establishment of an infective agent in or on a suitable host. An infection is the detrimental colonization of a host organism by a foreign species. The majority of interactions with microbes do not result in infection. The gold standard to determine exposure / infection is through serum tests (take one sample now and another sample some time later) 2 general mechanisms to control infections: resistance to infection. Pre-existing conditions that prevent or limit colonization: response to infection. Events that occur in host cells when the presence of bacteria is detected. They correspond to the evolutionary history of responses. Responses to infection are roughly equivalent to the development of different microbial responses. E. g. : major resistance for early cells = innate immunity (e. g. E. g. : major resistance for early cells = innate immunity (e. g. : physical barriers / membranes)

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