HLTB21H3 Study Guide - Final Guide: Mycobacterium Leprae, Leprosy, Cathar Yellow Cross

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Leprosy - basic information & etiology: caused by bacteria: mycobacterium leprae, occurs naturally only in humans, leprosy bacillus. Leprosy can affect all people: no one is ultimately susceptible, common in ages 10-14 and 25-44, rarely seen in infants, considered a disease of low virulence, bacilli are shed from the skin. History: may have originated in fear east asia, first documented in: India approximately 600 bc -> mentioned in: egypt 1550 bc -> papyrus document various writings, greece 320 bc -> mentioned in records, after the army of alexander the great returned from. Treatment: chaulmoogra nut, promin (1941, dapsone (1950s) controls growth of bacilli. Bcg (mycobacterium bovis) vaccine for tb: who recommends multidrug therapy (mdt, dapsone, rifampin and clofazamine. = less susceptibility to leprosy -> though no cross protection between tuberculosis and leprosy developed in india and works similarly to bcg immune tolerance and provoking a response that kills and clears m. leprae from the body =

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