BIO130H1- Final Exam Guide - Comprehensive Notes for the exam ( 62 pages long!)

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29 Mar 2018
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BIO130H1
Final EXAM
STUDY GUIDE
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BIO130 FINAL (Cellular Form and Function) 2016-03-09 12:37:00 AM
Readings: 120-144
Should be able to…
1. identify parts/functions of eukaryotic cell
2. place how these processes match with the parts
3. recognize techniques used in different experiments
Saccharomyces cerevisiae (budding yeast)
Single celled eukaryote
Has cell wall (tough protective outer coat)
Humans have multiple cell types e.g. skin cells, lung, epithelial cells
Lysosome:
Animal cell specific
Functions in the degradation of cell parts no longer needed
Extracellular Matrix (ECM):
Animal cell specific
Specialized material outside the cell
Very specific material
Other organisms can have things outside of cell, but animal cells
are very specific
Not found in animal cells: cell wall, vacuole, chloroplast
Can be found in other types of cell
Cell wall can be in bacteria, prokaryotes, single celled eukaryotes
Vacuole:
type 1= functions like animal lysosome in degradation
type 2= for storage
Cytoplasm: contents of cell outside of nucleus
Include organelles
Cytosol: aqueous part of cytoplasm
Includes ribosomes, cytoskeleton, protein structures
Lumen: inside of organelles
Functions of membranes
Compartmentalization
Scaffold for biochemical activities
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Selectively permeable membrane
Transporting solutes
Responding to external signals
Interactions between cells
Membrane bilayer
Fluid mosaic model
Hydrophobic tail
Hydrophilic/polar head
Phospholipids are moving around (fluid)
Mosaic because many different lipids and many different proteins
1 membrane is made of 2 layers/leaflets
Many different types of lipids
One type is a phospholipid
Many types of phospholipids
Polar head group that interacts with water and 2 hydrocarbon
hydrophobic tails that interact w other tails
o Spontaneously self-associate into a bilayer
Bilayer curls into a sphere (energetically favourable)
Liposome: artificial lipid bilayer (nanotechnology)
Study lipid properties
Membrane protein properties (add protein)
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