BCH210H1 Midterm: Study notes for midterm
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BCH210H1 Full Course Notes
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Document Summary
Chemicals of life: nucleic acids amino acids carbohydrates lipids steroids. The genetic code: nucleotides in triplets, each code for an amino acid. 20 naturally occurring residues: from 4 nucleotides. Monomers are zwitterions: one side negative, other side positive alpha carbon attached to nh3+ and coo- Amino acids with aliphatic side chains: glycine: -h, alanine: -ch3, valine: -isopropyl. Beta-branched: beta carbon attached to 1 h, leucine: - ch2-ch-2xch3. Basically valine"s r-group with an extra ch2. Not beta-branched: beta carbon attached to ch2, isoleucine: -c connected to both ch3 and ch2-ch3. Beta-branched: beta carbon attached to 1 h aliphatic hydroxyl side chains, serine: - ch2-oh. Oh = hydroxyl edge btw non-polar and polar: threonine: - ch connected to oh and ch3. Beta-branched: beta carbon attached to 1 h. Aromatic side chains: phenylalanine: -ch2-benzene, tyrosine: -ch2-benzene-oh, tryptophan: -ch2-indole ring, cysteine: -ch2-sh sulfur. Rough pka values of amino acid side chains the ph at which proton dissociates.