Biochemistry 2280A Study Guide - Quiz Guide: Chemical Polarity, Polymerization, Pyrimidine

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Nucleotide are: nitrogen-contain baes which include adenine, thymone, Guanine and cytosine: five-carbon sugar -> deoxyribose, phosphate group, supply of nucleoside triphosphates needed for nucleic acid synthesis, by convention the carbons in the sugar are labelled 1" to 5". Nucleotides are covently linked by a sugar phosphate backbone in order to form nucleic acids. The dna strand has a 5" end due to a 5" phosphate group and a 3" end due to a 3" hydroxyl. Phosphodiester bonds are formed between the 5" and 3" carbons in the deoxyribose sugar. Purines are double ringed and examples of this are adenine and gaunine. Pyrimidines are single ringed and examples of this are thymine and cytosine. A purine always pairs with a pyrimidine -> allows there to be constant sugar-phosphate backbone and no distortion. The a-t base pairing is weaker than the g-c pair.

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