Biology 2581B Study Guide - Quiz Guide: Zebrafish, Swim Bladder, Model Organism

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Zebrafish are a good model organism because they are small, can be stored in large numbers in fish tanks, produce large batches of embryos (100 a week) and are easy to breed. They also have relatively transparent embryos so easy to score their phenotypes and they have a sequenced genome. However, their generation time is 2-3 months so this isn"t very short compared to some model organisms. Also, they have a fairly long genome, which makes sequencing more difficult. Despite this, they have a few advantages over other model organisms. They are vertebrates so their organs and immune system is very comparable to ours. Also, it is possible to do haploid development with zebrafish. Normally if you want to study a mutation you have to cross two carriers together to get homozygous offspring. With haploid development you can bypass this so if the mother is a carrier you get mutants instead of .

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