Biology 2581B Study Guide - Quiz Guide: Coiled Coil, Dynactin, Alpha Helix
3 Jun 2020
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Since defined nucleation: - ends @ mtocs give co-ordinates for trafficking / organelle distribution (i. e. consistent directionality can use same motor protein. + end tracking: kinesins: superfamily 14 families: kinesin like proteins (klps: 14 the directed. 14 families: group by motor domain position: standard by numbering. Most > + end, n terminal motor: kinesin-14: e. g. drosophila ncd, human hset, c terminal motor. Internal motor: 5: e. g. bimc in aspergillus, human eg5. Kinesin-1: dimer by coiled coil: tail association > double dimer (2 heads) End directed mt motors: among fastest. 2-3 heavy chains each motor domain: each heavy multiple associated light chains, homodimers 2 large motor domains, functionality: Axonemal: cilia - many /cell- e. g. tracheal mucous flow flagella c. 1 /cell (in eukarya) e. g. sperm, heterodimers / trimers that # motor domains, from centriole with mt triplets in cartwheel. Basal body anchor > plasmalemma: hence no. motile elements limited by centriole no. Core mts = axoneme: arrangement 9 + 2:
