Biology 3592A Study Guide - Twin Study, Schizophrenia, Epigenetics

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4 Dec 2014
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Will be returned this week in tutorial. Due wednesday november 5, 2014 at the start of tutorial. Cause of premature mortality in almost 2/3 of all individuals. Inheritance generally does not follow mendelian pattern. Family members share a greater proportion of genetics than random individuals. Family members also share a greater proportion of environmental exposures than do random individuals. Height, blood pressure, body mass index http://www. ashg. org/images/height%20graph. jpg. Concordance two related individuals in family have the same disease. Discordance when only member of the pair of relatives is affected and the other is not. Discordance for a phenotype between relatives who share a genotype may occur. Concordance for a phenotype between relatives who show different genotypes may occur. The larger r the greater the familial aggregation. Population prevalence important because common disease can show aggregation due to chance. 1 = relative no more likely than general population. Patients of a disease compared to normal controls.

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