Biology 1002B Study Guide - Final Guide: Taq Polymerase, Exon Shuffling, Gene Knockdown
17 Apr 2016
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Lecture 18: basic mechanism of propagation of action potentials in neurons, very negative inside and positive outside, an influx of positive ions enters the cell causing depolarization and a action potential. Lecture 19: use of information at the national center for biotechnology information for pcr. Lecture 20: current trend in cost of dna sequencing. Gsa for lecture 21: role of transcriptomics. The study of a complete set of transcripts in a cell: basic mechanism of dna microarrays to determine relative gene expression. Gene knockout: replace normal gene with a defective gene that cannot work. Gene knockdown: stop or decrease gene expression by using rnai interference, role of proteomics. Complete set of proteins in an organism"s genome. Duplication in pufferfish: chromosomes are pretty much uniform in type from common ancestor, this is due to complete duplication of ancestor"s genome. Mobile elements in humans: translocations and fusions led to an array of genes in chromosomes from common ancestor, overall strategy of metagenomics.
